- The tattoos seen in Silk Stalkings (1991) and Sliders (1995) are real. Sheppard has at least four (both upper arms, left chest, and shoulder blade), all of dragons.
- Played the same character, at a younger age, as his father William Morgan Sheppard in episodes of The Impossible Astronaut (2011), Broken Bird (2009), and the movie Mysterious Island (2010).
- He has been sober since 1990.
- Like his father William Morgan Sheppard, he has made guest appearances on Star Trek: Voyager (1995), Charmed (1998) and Doctor Who (2005).
- Started acting at the age of 27.
- Was a successful session Musician and toured with many bands from the age of 15.
- He is the only actor to appear in ''Supernatural'' and ''Doctor Who (2005)''.
- Has worked with actor Adam Baldwin in 5 projects: Lover's Knot (1995), Farewell, My Love (2000), Firefly (2002), Evil Eyes (2004), and Chuck (2007).
- Son of William Morgan Sheppard.
- In December 2023, he almost died when he had a 100% blockage in his LAD (left anterior descending artery), known as the widowmaker type of heart attack. He was immediately treated and brought back to life 4 times in Los Angeles.
- Sons Max and William and daughter Isabella Rose.
- His television work includes guest-staring and doing recurring roles on such shows as The The X Files (1993), Las Vegas (2003), CSI: NY (2004), Medium (2005), Battlestar Galactica (2004), Leverage (2008), Supernatural (2005), and others.
- Lives in Los Angeles.
- Shares a birthday anniversary (month and day only) with fellow Star Trek actor Colm Meaney.
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