Ada Yonath

Ada Yonath
Rayuwa
Haihuwa	Jerusalem, 22 ga Yuni, 1939 (85 shekaru)
ƙasa	Isra'ila
Karatu
Makaranta	Jami'ar Ibraniyawa ta Kudus Weizmann Institute of Science (en)
Thesis director	Wolfie Traub (en)
Harsuna	Ibrananci Turanci
Sana'a
Sana'a	molecular biologist (en) , chemist (en) , university teacher (en) , crystallographer (en) , biochemist (en) , scientist (en) da researcher (en)
Wurin aiki	Weizmann Institute of Science (en)
Employers	University of Chicago (en) Q102212738
Kyaututtuka	gani Israel Prize  (2002) Nobel Prize in Chemistry  (2009) Harvey Prize  (2002) Paul Ehrlich and Ludwig Darmstaedter Prize  (2007) Wilhelm Exner Medal  (2010) Wolf Prize in Chemistry  (2006) L'Oréal-UNESCO Award For Women in Science  (2008) Albert Einstein World Award of Science  (2008) Massry Prize  (2004) Louisa Gross Horwitz Prize  (2005) Silver Medal of the Chairman of the Senate  (2012) X-ray badge  (2014) The EMET Prize for Art, Science and Culture  (2006) honorary doctor of Carnegie-Mellon University honorary doctor of the University of Chile Honorary doctor of the Technical University of Berlin F. A. Cotton Medal  (2002) honorary doctor of the University of Hamburg EMBO Membership Esther Hoffman Beller Lectureship  (2021) Erna Hamburger Prize  (2011) Foreign Member of the Royal Society  (2020) Rothschild prize Marie Curie Medal  (2011) honorary doctorate from Joseph Fourier University  (31 ga Maris, 2015)
Wanda ya ja hankalinsa	William Lipscomb (en)
Mamba	National Academy of Sciences (en) European Academy of Sciences and Arts (en) Israel Academy of Sciences and Humanities (en) Pontifical Academy of Sciences (en) American Academy of Arts and Sciences (en) European Molecular Biology Organization (mul) German Academy of Sciences Leopoldina (en) The Royal Society (mul)

Ada E. Yonath ( Hebrew ,he ; an haife shi 22 Yuni 1939) ^[1] yar wasan crystallographer ta Isra'ila ce kuma wacce ta ba da lambar yabo ta Nobel a Chemistry, wacce aka fi sani da aikinta na majagaba akan tsarin ribosomes . Ita ce darekta na yanzu na Cibiyar Helen da Milton A. Kimmelman don Tsarin Biomolecular da Majalisar Cibiyar Kimiyya ta Weizmann .

A shekara ta 2009, Yonath ta sami lambar yabo ta Nobel a fannin ilmin sunadarai tare da Venkatraman Ramakrishnan da Thomas A. Steitz saboda karatunta kan tsarin da aikin ribosome, ta zama mace ta farko ta Isra'ila da ta lashe Kyautar Nobel daga cikin 'yan wasan Nobel goma na Isra'ila, mace ta farko daga Gabas ta Tsakiya da ta lashe lambar yabo ta Nóbel a fannin kimiyya, kuma mace ta farko a cikin shekaru 45 da ta lashe Kyautar Nobel ta ilmin sunada.^[2]

An yarda da Yonath a makarantar sakandare ta Tichon Hadash kodayake mahaifiyarta ba ta iya biyan kuɗin karatun ba. Ta ba da darussan lissafi ga ɗalibai a sakamakon haka.^[3] Yayinda take matashiya, ta ce masanin kimiyya na Poland da kuma 'yan asalin Faransa Marie Curie ne suka yi mata wahayi.^[4] Koyaya, ta jaddada cewa Curie, wanda tun tana yarinya ta yi sha'awarta bayan karanta tarihin rayuwarta, ba "alamu ba ne". Ta koma Urushalima don kwaleji, ta kammala karatu daga Jami'ar Ibrananci ta Urushalima tare da digiri na farko a ilmin sunadarai a shekarar 1962, da kuma digiri na biyu a ilmin ilmin sunayensu a shekarar 1964. A shekara ta 1968, ta sami digirinta na PhD daga Cibiyar Kimiyya ta Weizmann don nazarin X-ray crystallographic akan tsarin collagen, tare da Wolfie Traub a matsayin mai ba da shawara na PhD. ^[5][6][7]

Tana da 'yar daya, Hagit Yonath, likita a Cibiyar Kiwon Lafiya ta Sheba, da kuma jikoki, Noa . ^[8] Ita ce dan uwan mai fafutukar adawa da mamayewa Ruchama Marton .

Yonath ya karbi mukamai na postdoctoral a Jami'ar Carnegie Mellon (1969) da MIT (1970). Yayinda take postdoc a MIT ta shafe wani lokaci a dakin gwaje-gwaje na William N. Lipscomb, Jr. wanda ya lashe kyautar Nobel ta 1976 na Jami'ar Harvard inda aka yi wahayi zuwa gare ta don bin manyan tsari.

A shekara ta 1970, ta kafa abin da ya kasance kusan kusan shekaru goma kawai dakin gwaje-gwaje na furotin a Isra'ila. Sa'an nan, daga 1979 zuwa 1984 ta kasance jagorar rukuni tare da Heinz-Günter Wittmann a Cibiyar Max Planck don Kwayoyin Kwayoyin Kwayar halitta a Berlin. Ta kasance farfesa mai ziyara a Jami'ar Chicago a 1977-78. ^[9] Ta jagoranci Cibiyar Bincike ta Max-Planck a DESY a Hamburg, Jamus (1986-2004) tare da ayyukanta na bincike a Cibiyar Weizmann .

Yonath tana mai da hankali kan hanyoyin da ke haifar da furotin biosynthesis, ta hanyar ribosomal crystallography, layin bincike da ta fara sama da shekaru ashirin da suka gabata duk da shakku mai yawa na al'ummar kimiyya ta duniya.^[10] Ribosomes suna fassara RNA zuwa furotin kuma saboda suna da tsari daban-daban a cikin ƙwayoyin cuta, idan aka kwatanta da eukaryotes, kamar ƙwayoyin ɗan adam, galibi suna da manufa ga maganin rigakafi. A cikin 2000 da 2001, ta ƙayyade cikakkun tsarin ƙuduri na duka sassan ribosomal kuma an gano su a cikin ribosome asymmetric, yankin daidaitawa na duniya wanda ke ba da tsarin kuma kewaya tsarin polypeptide polymerization. Sakamakon haka, ta nuna cewa ribosome wani Ribozyme ne wanda ke sanya substrates dinsa a cikin Stereochemistry wanda ya dace da samar da haɗin peptide da kuma catalysis na substrate. A shekara ta 1993 ta hango hanyar da sunadarai masu tasowa suka dauka, wato ramin ribosomal, kuma kwanan nan ta bayyana abubuwan da ke ba da damar shiga cikin kamawa, ƙofar, tsarin intra-cellular da narkewar sarkar fataucin cikin sarkar su.

Bugu da ƙari, Yonath ya bayyana hanyoyin aiki na fiye da Magungunan rigakafi daban-daban guda ashirin da ke da niyya ga ribosome, hanyoyin haskakawa na juriya da hadin kai, ya fassara tushen tsari don zaɓin maganin rigakafi kuma ya nuna yadda yake taka muhimmiyar rawa a cikin amfani na asibiti da tasirin warkewa, don haka ya shirya hanyar ƙirar magungunan da ke da tsarin.

Don ba da damar ribosomal crystallography Yonath ya gabatar da sabuwar fasaha, cryo bio-crystallography, wanda ya zama al'ada a cikin ilmin halitta na tsari kuma ya ba da izinin ayyukan da ba a ɗauka ba.^[11]

A Cibiyar Weizmann, Yonath ita ce mai rike da Martin S. da Helen Kimmel Farfesa.

Ta yi kira da a saki dukkan fursunonin Hamas ba tare da wani sharadi ba, tana mai cewa "tsayar da Palasdinawa yana ƙarfafawa da ci gaba da motsa su don cutar da Isra'ila da 'yan ƙasa ... da zarar ba mu da fursunoni da za su saki ba za su sami dalilin satar sojoji ba".

Yonath memba ne na Kwalejin Kimiyya ta Kasa ta Amurka; Kwalejin Fasaha da Kimiyya ta Amurka; Cibiyar Kimiyya da Kimiyya da Dan Adam ta Isra'ila; Kwalejin Kimiyya da Fasaha ta Turai da Kungiyar Kwalejin Kwalejin Turai. A ranar Asabar, 18 ga Oktoba 2014, Paparoma Francis ya kira Farfesa Yonath a matsayin memba na Kwalejin Kimiyya ta Pontifical . ^[12]

Kyaututtuka da girmamawa sun hada da:

• A shekara ta 2002, Kyautar Isra'ila
• A shekara ta 2002, Kyautar Harvey
• A shekara ta 2004, Kyautar Massry
• A shekara ta 2004, lambar yabo ta Paul KarrerMedal na zinariya na Paul Karrer
• A shekara ta 2005, Kyautar Louisa Gross Horwitz
• A shekara ta 2006, Wolf Prize a cikin Chemistry tare da George Feher .
• A shekara ta 2006, Kyautar Rothschild a Kimiyya ta Rayuwa .
• A shekara ta 2006, Kyautar EMET don Fasaha, Kimiyya da Al'adu a Kimiyya ta Rayuwa, tare da Farfesa Peretz Lavie (Medicine) da Farfesa Eli Keshet (Biology)
• A shekara ta 2007, Paul Ehrlich da Ludwig Darmstaedter Prize tare da Harry Noller
• A shekara ta 2008, lambar yabo ta Albert Einstein World Award of Science saboda gudummawar da ta bayar ga furotin biosynthesis a fagen ribosomal crystallography da gabatar da sabbin fasahohi a cikin cryo bio-crystallography.^[13]
• A shekara ta 2009, lambar yabo ta Nobel a fannin ilmin sunadarai (tare da Thomas Steitz da Venkatraman Ramakrishnan). ^[14] Ita ce mace ta farko ta Isra'ila da aka ba ta Kyautar Nobel.
• A shekara ta 2010, lambar yabo ta Wilhelm Exner ^[15]
• A cikin 2011, lambar yabo ta Marie Curie da kungiyar Polish Chemical Society ta bayar ^[16]
• A shekara ta 2013 ta zama memba na Kwalejin Kimiyya ta Leopoldina ta Jamus . ^[17]
• A shekara ta 2015, an ba ta lambar yabo ta Doctorates daga Jami'ar Kudancin California, Jami'ar De La Salle, Manila / Philippines; Jami'ar Joseph Fourier, Grenoble / Faransa; Jami'an Kiwon Lafiya na Lodz, Lodz / Poland; da Jami'ar Warwick, Burtaniya. ^[18][19][20]
• A cikin 2018, an ba ta lambar yabo ta Doctorate daga Jami'ar Carnegie Mellon ^[21]
• A cikin 2020, an zabe ta memba na kasashen waje na Royal Society ^[22]
• A shekara ta 2023, an ba ta lambar yabo ta Doctorate daga Jami'ar Jagiellonian . ^[23]

• Mata na Isra'ila
• Tarihin ilmin halitta na RNA
• Jerin masu karɓar kyautar Isra'ila
• Jerin mata masu lashe kyautar Nobel
• Jerin masu lashe kyautar Nobel ta Isra'ila
• Jerin wadanda suka lashe kyautar Nobel ta Yahudawa
• Jerin masu fafutukar zaman lafiya
• Jerin masu ilimin halitta na RNA
• Jerin lokaci na mata a kimiyya
• Mata a cikin ilmin sunadarai

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Wikimedia Commons on Ada Yonath

• "Mai amfani da APS yana raba "Nobel na Isra'ila" don ilmin sunadarai", daga Argonne National Laboratory Advanced Photon Source (APS), Ma'aikatar Makamashi ta Amurka
• Shafin hukuma na Kyautar Louisa Gross Horwitz
• Cibiyar Kimiyya ta Weizmann, Yonath-Site
• Jerin wallafe-wallafen Ada Yonath
• Magana game da Ada Yonath a taron Origins 2011
• Ada E. Yonatha kan Nobelprize.org

Samfuri:Israeli Nobel laureatesSamfuri:Nobel Prize in Chemistry Laureates 2001-2025Samfuri:2009 Nobel Prize WinnersSamfuri:Wolf Prize in ChemistrySamfuri:Albert Einstein World Award of Science LaureatesSamfuri:FRS 2020

1. ↑ "Israel Prize Official Site (in Hebrew) – Recipient's C.V."
2. ↑ "Transcript of the telephone interview with Ada E. Yonath immediately following the announcement of the 2009 Nobel Prize in Chemistry". nobelprize.org. 6 October 2015. Archived from the original on 6 October 2015. Retrieved 9 March 2021.
3. ↑ Siegel-Itzkovich, Judy (17 January 2012). "Former 'village fool' takes the prize – Science and Environment – Jerusalem Post". fr.jpost.com. Archived from the original on 17 January 2012. Retrieved 9 March 2021.
4. ↑ "ISRAEL21c – Uncovering Israel". Israel21c. 5 October 2011. Archived from the original on 24 June 2016.
5. ↑ "(IUCr) European Crystallography Prize". Journal of Applied Crystallography. 33 (4): 1195. August 2000. doi:10.1107/S0021889800008281.
6. ↑ Traub, Wolfie; Yonath, Ada (1966). "Polymers of Tripeptides as Collagen Models .I. X-RAY Studies of Poly (L-PROLYL-GLYCYL-L-PROLINE) and related Polytripeptides". Journal of Molecular Biology. 16 (2): 404–14. doi:10.1016/S0022-2836(66)80182-1. PMID 5954171.
7. ↑ Yonath, Ada; Traub, Wolfie (1969). "Polymers of Tripeptides as Collagen Models .4. Structure Analysis of Poly (L-PROLYL-GLYCYL-L-PROLINE)". Journal of Molecular Biology. 43 (3): 461–77. doi:10.1016/0022-2836(69)90352-0. PMID 5401228.
8. ↑ Ilani, Ofri (3 December 2009). "Israel's Prof. Ada Yonath wins Nobel Prize for Chemistry – Haaretz – Israel News". haaretz.com. Archived from the original on 3 December 2009. Retrieved 9 March 2021.
9. ↑ anonymous. "New chemistry Nobelist was UChicago visiting prof, conducted research at Argonne". uchicago.edu. Archived from the original on 2010-06-10. Retrieved 2017-11-27.
10. ↑ "The Nobel Prize in Chemistry 2009 – Speed Read". nobelprize.org.
11. ↑ Hope, H.; Frolow, F.; von Böhlen, K.; Makowski, I.; Kratky, C.; Halfon, Y.; Danz, H.; Webster, P.; Bartels, K. S.; Wittmann, H. G.; Yonath, A. (1 April 1989). "Cryocrystallography of ribosomal particles". Acta Crystallographica Section B: Structural Science. International Union of Crystallography (IUCr). 45 (2): 190–199. Bibcode:1989AcCrB..45..190H. doi:10.1107/s0108768188013710. ISSN 0108-7681. PMID 2619959.
12. ↑ "Rinunce e nomine". vatican.va (in Italiyanci). Archived from the original on 22 October 2014.
13. ↑ "Albert Einstein World Award of Science 2008". Archived from the original on 4 March 2014.
14. ↑ "Nobel Prize in Chemistry 2009". Nobel Foundation. Archived from the original on 10 October 2009. Retrieved 7 October 2009.
15. ↑ "Medalists Archive – ALL MEDALISTS SINCE 1921". Wilhelm Exner Medaillen Stiftung (in Turanci). Retrieved 9 March 2021.
16. ↑ "Laureaci Medali i Nagród PTChem". Retrieved 2020-02-22.
17. ↑ "Ada Yonath". German Academy of Sciences Leopoldina. Retrieved 26 May 2021.
18. ↑ "Past Recipients – Honorary Degrees". honorarydegrees.usc.edu. Retrieved 2024-06-07.
19. ↑ "Honorary Graduand Orations – Summer 2015". www2.warwick.ac.uk.
20. ↑ "Uniwersytet Medyczny w Łodzi". www.umed.pl. Archived from the original on 4 March 2016. Retrieved 1 May 2015.
21. ↑ "Commencement Speakers and Honorary Degree Recipients – Leadership – Carnegie Mellon University". www.cmu.edu (in Turanci). Retrieved 2018-09-21.
22. ↑ "Ada Yonath". Royal Society. Retrieved 19 September 2020.
23. ↑ "Honorary Doctorate". en.uj.edu.pl. Retrieved 28 May 2023.