posaconazole (Q906453)

From Wikidata

Jump to navigation Jump to search

pharmaceutical drug

Posaconazole

Language	Label	Description	Also known as
default for all languages	No label defined
English	posaconazole	pharmaceutical drug	Posaconazole

Statements

type of chemical entity

0 references

1 reference

27 February 2018

4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

0 references

1 reference

Posaconazole (English)

language of work or name

publication date

17 November 2015

chemical structure

Posaconazole Formulae.png
2,136 × 4,140; 32 KB

1 reference

imported from Wikimedia project

German Wikipedia

700.329708 dalton

1 reference

language of work or name

NCGC00185736-01 (English)

19 September 2016

chemical formula

C₃₇H₄₂F₂N₈O₄

1 reference

language of work or name

NCGC00185736-01 (English)

19 September 2016

canonical SMILES

CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F

1 reference

Posaconazole (English)

3 October 2018

isomeric SMILES

CC[C@@H]([C@H](C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5C[C@](OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F

1 reference

Posaconazole (English)

3 October 2018

active ingredient in

1 reference

15 February 2018

Posaconazole Sp

1 reference

European Medicines Agency product number

EMEA/H/C/000611

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000611/human_med_000980.jsp

22 March 2017

medical condition treated

1 reference

Drug Indications Extracted from FAERS

2 October 2018

significant drug interaction

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

central respiratory depression

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

sinus bradycardia

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

acute kidney injury

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

dasatinib monohydrate

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

muscular disease

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

muscular disease

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

central respiratory depression

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

long QT syndrome

1 reference

sourcing circumstances

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category B3

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Posaconazole

17 May 2017

subject has role

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

trypanocidal agent

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

14-alpha demethylase inhibitor

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

2 references

NCI Thesaurus ID

C61500

1 reference

Global Substance Registration System

15 February 2018

Commons category

Posaconazole

0 references

Identifiers

InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

1 reference

Posaconazole (English)

3 October 2018

RAGOYPUPXAKGKH-XAKZXMRKSA-N

2 references

Global Substance Registration System

15 February 2018

3 October 2018

Posaconazole (English)

CAS Registry Number

3 references

language of work or name

Posaconazole (English)

publication date

17 November 2015

Global Substance Registration System

15 February 2018

RAGOYPUPXAKGKH-XAKZXMRKSA-N

CAS Common Chemistry

10 April 2021

https://commonchemistry.cas.org/detail?cas_rn=171228-49-2

0 references

2 references

Posaconazole (English)

3 October 2018

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

mapping relation type

3 references

imported from Wikimedia project

English Wikipedia

ChEBI release 2021-03-01

matched by identifier from

International Chemical Identifier

InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

UniChem compound ID

1 reference

splash10-0udi-0112123900-47df3b00c4a4865b0d1a

0 references

DSSTox substance ID

1 reference

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol (English)

CAS no.: 171228-49-2 (English)

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol (English)

CAS no.: 171228-49-2 (English)

1 reference

language of work or name

Posaconazole (English)

publication date

17 November 2015

MeSH descriptor ID

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

1 reference

Global Substance Registration System

15 February 2018

1 reference

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

3 references

language of work or name

POSACONAZOLE (English)

19 January 2016

Global Substance Registration System

15 February 2018

matched by identifier from

RAGOYPUPXAKGKH-XAKZXMRKSA-N

MedlinePlus drug identifier

route of administration

oral administration

0 references

route of administration

intravenous injection

0 references

1 reference

language of work or name

POSACONAZOLE (English)

19 January 2016

Probes And *** ID

0 references

1 reference

1 reference

language of work or name

Posaconazole (English)

19 January 2016

0 references

1 reference

6 April 2020

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

WikiProjectMed ID

0 references

Sitelinks

Wikipedia(18 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Posaconazole

Retrieved from "https://www.wikidata.org/w/index.php?title=Q906453&oldid=2306134559"