sacwinafir (Q422654)

inferred from SMILES ^Saesneg

defnydd

cyffur meddygol

0 ffynonellau

adeiledd gemegol

Saquinavir structure.svg
512 × 521; 10 KB

0 ffynonellau

màs

670.384 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

(2S)-N-[(2S,3R)-4-[(3S,4aS,8aR)-3-[(tert-butylamino)-oxomethyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-[[oxo(2-quinolinyl)methyl]amino]butanediamide ^Saesneg

19 Hydref 2016

stereoisomer of ^Saesneg

1 ffynhonnell

inferred from InChIKey ^Saesneg

fformwla gemegol

C₃₈H₅₀N₆O₅

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(C(CC3=CC=CC=C3)NC(=O)C(CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

isomeric SMILES ^Saesneg

CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

defined daily dose ^Saesneg

1.8 gram

dull gweini

gweini genau

1 ffynhonnell

https://www.whocc.no/atc_ddd_index/?code=J05AE01

cynhwysyn actif yn

Fortovase ^Saesneg

1 ffynhonnell

European Medicines Agency product number ^Saesneg

EMEA/H/C/000178

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000178/human_med_000799.jsp

22 Mawrth 2017

Invirase ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

203674

14 Chwefror 2018

World Health Organisation international non-proprietary name ^Saesneg

saquinavir (Saesneg)

1 ffynhonnell

ChEBI

ChEBI ID ^Saesneg

63621

syndrom diffyg imiwnolegol caffaeledig

saquinavir (Saesneg)

19 Hydref 2016

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000148419

feirws imiwnoddiffygiant dynol

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

NDF-RT

N0000148419

13 Rhagfyr 2016

significant drug interaction ^Saesneg

bosentan

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

carbamasepin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

riffabwtin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

riffampisin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

riffapentin

1 ffynhonnell

High-priority drug–drug interactions for use in electronic health records ^Saesneg

methadon

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

erythromycin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

foriconasol

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

clarithromycin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

fenlaffacsin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

bwprenorffin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rosuvastatin ^Saesneg

side effect ^Saesneg

rhabdomyolysis ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

rosuvastatin ^Saesneg

side effect ^Saesneg

muscular disease ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

warffarin

side effect ^Saesneg

retroperitoneal hemorrhage ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ciclosporin

side effect ^Saesneg

methiant yr arennau

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ciclosporin

side effect ^Saesneg

cholestasis ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ciclosporin

side effect ^Saesneg

paresthesia ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

posaconazole ^Saesneg

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

cetoconasol

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

established ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atorfastatin

side effect ^Saesneg

rhabdomyolysis ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

atorfastatin

side effect ^Saesneg

muscular disease ^Saesneg

1 ffynhonnell

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

ffosffenytoin

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

tacrolimws

side effect ^Saesneg

long QT syndrome ^Saesneg

1 ffynhonnell

hypothetically ^Saesneg

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

LiverTox likelihood score ^Saesneg

LiverTox toxicity likelihood category D ^Saesneg

1 ffynhonnell

LiverTox ^Saesneg

8 Ebrill 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Saquinavir

last update ^Saesneg

1 Medi 2017

rôl y pwnc

HIV protease inhibitors ^Saesneg

2 ffynonellau

NDF-RT ^Saesneg

5 Mawrth 2018

15 Mawrth 2018

cytochrome P-450 CYP3A inhibitors ^Saesneg

1 ffynhonnell

15 Mawrth 2018

0 ffynonellau

1 ffynhonnell

ChEBI ID ^Saesneg

1 ffynhonnell

Saquinavir

0 ffynonellau

catalog

CAS COVID-19 Anti-Viral Candidate Compounds ^Saesneg

0 ffynonellau

Identifiers

InChI

InChI=1S/C38H50N6O5/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49)/t26-,27+,30-,31-,32-,33+/m0/s1

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

127779-20-8

2 ffynonellau

UNII ^Saesneg

saquinavir (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

9 Ebrill 2021

https://commonchemistry.cas.org/detail?cas_rn=127779-20-8

ChemSpider ID ^Saesneg

390016

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

390016

Saquinavir (Saesneg)

19 Tachwedd 2016

PubChem CID ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

Reaxys registry number ^Saesneg

5469491

1 ffynhonnell

ChEBI

ChEBI ID ^Saesneg

63621

saquinavir (Saesneg)

19 Hydref 2016

ChEBI ID ^Saesneg

63621

mapping relation type ^Saesneg

exact match ^Saesneg

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL114

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

International Chemical Identifier ^Saesneg

InChI

ChEMBL ID ^Saesneg

CHEMBL114

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL114

SAQUINAVIR (Saesneg)

19 Tachwedd 2016

SureChEMBL ID ^Saesneg

SCHEMBL6881

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey ^Saesneg

UniChem compound ID ^Saesneg

16361

1 ffynhonnell

UniChem ^Saesneg

MassBank accession ID ^Saesneg

MSBNK-Waters-WA001494

0 ffynonellau

MSBNK-Waters-WA001495

0 ffynonellau

MSBNK-Waters-WA001496

0 ffynonellau

MSBNK-Waters-WA001497

0 ffynonellau

dynodwr HSDB

7161

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

SAQUINAVIR (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID6044012

2 ffynonellau

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

InChIKey ^Saesneg

Dynodwr Drugbank (Alberta)

DSSTOX compound identifier ^Saesneg

DTXCID4024012

0 ffynonellau

LiverTox ID ^Saesneg

0 ffynonellau

1 ffynhonnell

DrugBank ^Saesneg

DB01232

dynodwr Llawlyfr Ffarmacoleg Ligand

Saquinavir (Saesneg)

dyddiad cyhoeddi

17 Tachwedd 2015

4813

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

4813

saquinavir (Saesneg)

19 Tachwedd 2016

Saquinavir

0 ffynonellau

Cod MeSH

D03.633.100.531.770

0 ffynonellau

D03.633.100.810.900

0 ffynonellau

RxNorm ID ^Saesneg

83395

1 ffynhonnell

UNII ^Saesneg

saquinavir (Saesneg)

Dynodwr Drugbank (Alberta)

19 Tachwedd 2016

DB01232

1 ffynhonnell

InChIKey ^Saesneg

dynodwr HMDB

HMDB0015362

0 ffynonellau

UNII ^Saesneg

2 ffynonellau

UNII ^Saesneg

saquinavir (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

MedlinePlus drug identifier ^Saesneg

a696001

0 ffynonellau

PatientsLikeMe treatment ID ^Saesneg

saquinavir

0 ffynonellau

NIAID ChemDB ID ^Saesneg

1 ffynhonnell

1 ffynhonnell

UNII ^Saesneg

saquinavir (Saesneg)

19 Tachwedd 2016

Probes And *** ID ^Saesneg

PD012384

0 ffynonellau

DrugCentral ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

ChEBI ID ^Saesneg

dynodwr Encyclopædia Britannica Online

saquinavir (Saesneg)

19 Hydref 2016

0 ffynonellau

electronic Essential Medicines List medicine ID ^Saesneg

489

0 ffynonellau

topic/saquinavir

enwyd fel

saquinavir

0 ffynonellau

dynodwr Freebase

/m/074sdc

1 ffynhonnell

dynodwr Microsoft Academic

Freebase Data Dumps ^Saesneg

28 Hydref 2013

0 ffynonellau

1 ffynhonnell

KBpedia ^Saesneg

9 Gorffennaf 2020

2776937687

0 ffynonellau

2908629294

0 ffynonellau

OpenAlex ID ^Saesneg

1 ffynhonnell

OpenAlex ^Saesneg

26 Ionawr 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID ^Saesneg

1C6Z

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1C6Z

1C6Z (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3D1Y

3D1Y (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3S56

3S56 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3TKG

3TKG (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4Q5M

4Q5M (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3NDT

3NDT (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

5KR2

5KR2 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3TL9

3TL9 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2NNP

2NNP (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2NNK

2NNK (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3PWR

3PWR (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3PWW

3PWW (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3OXC

3OXC (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

5KQX

5KQX (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3N3I

3N3I (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3EKQ

3EKQ (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2NMZ

2NMZ (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

2NMY

2NMY (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3CYX

3CYX (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3UFN

3UFN (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3D1X

3D1X (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4QGI

4QGI (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3K4V

3K4V (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3NDU

3NDU (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3EL4

3EL4 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1HXB

1HXB (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1FB7

1FB7 (Saesneg)

19 Hydref 2016

UMLS CUI ^Saesneg

C0286738

1 ffynhonnell

UNII ^Saesneg

saquinavir (Saesneg)

19 Tachwedd 2016

1 ffynhonnell

inferred by common MeSH mappings on source and on Wikidata ^Saesneg

UMLS 2023 ^Saesneg

25 Mai 2023

0 ffynonellau

WikiProjectMed ID ^Saesneg

Saquinavir

0 ffynonellau

WordNet 3.1 Synset ID ^Saesneg

04300746-n

1 ffynhonnell